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Apart from spinning things maybe not spinning, why would it not work?
Big one would be capacitors. They don’t last forever and with time with work less efficiently, or not at all. They can leak and corrode the board.
Tin whiskers could be a potential issue as well.
But more likely to dry up/leak if you use the thing for 20 years than if you don’t, because of heat.
Electronics degrade over time. Like everything.